Description

4-(3-Ethoxycarbonylpiperidine)Carboxamidophenylboronic Acid, Pinacol Ester is a sophisticated boronic ester derivative, a crucial building block in modern synthetic organic chemistry. This compound is valued for its role as a protected boronic acid, offering enhanced stability and solubility for use in cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules and active pharmaceutical ingredients (APIs).

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and boronic acids, essential for constructing biaryl motifs in drug discovery.
• Pharmaceutical Intermediate Synthesis: Serves as a critical precursor in the multi-step synthesis of novel therapeutic compounds, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research & Development: Used in the creation of advanced crop protection agents and herbicides that require specific aryl-piperidine structural frameworks.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors and light-emitting materials for electronic displays.
• Medicinal Chemistry & Library Synthesis: Facilitates high-throughput parallel synthesis for generating diverse compound libraries for biological screening.
• Process Chemistry & Scale-Up: Provides a stable and handleable form of the reactive boronic acid for optimized manufacturing processes under GMP conditions.

Basic Information

Product Name	4-(3-Ethoxycarbonylpiperidine)Carboxamidophenylboronic Acid, Pinacol Ester
CAS No.	850411-14-2
Molecular Formula	C21H31BN2O5
Molecular Weight	402.29 g/mol
Synonyms	4-[[(3-Ethoxycarbonyl-1-piperidinyl)carbonyl]amino]benzeneboronic Acid Pinacol Ester; 4-(3-(Ethoxycarbonyl)piperidine-1-carboxamido)phenylboronic Acid Pinacol Ester; B-[4-[[(3-Ethoxycarbonyl-1-piperidinyl)carbonyl]amino]phenyl]-5,5-dimethyl-1,3,2-dioxaborinane; 4-(3-Ethoxycarbonylpiperidine-1-carboxamido)phenylboronic Acid Pinacol Ester; Boronic Acid, B-[4-[[(3-ethoxycarbonyl-1-piperidinyl)carbonyl]amino]phenyl]-, 5,5-dimethyl-1,3,2-dioxaborinane Ester; CAS 850411-14-2; Pharmaceutical Intermediate 850411-14-2
EINECS	Contact for details

Quality Control

Our 4-(3-Ethoxycarbonylpiperidine)Carboxamidophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity suitable for demanding research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.