Description

2-[4-([1,3]Dioxolan-2-Ylmethoxy)-Phenyl]-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is a high-value, protected boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its primary value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex aromatic and heteroaromatic systems.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific biaryl motifs for bioactivity.
• Material Science: Precursor for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and organic photovoltaics, where controlled conjugation is paramount.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the construction of molecular probes and tags for studying biological processes and target engagement.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic pathways in both academic laboratories and industrial R&D centers.

Basic Information

Product Name	2-[4-([1,3]Dioxolan-2-Ylmethoxy)-Phenyl]-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
CAS No.	850411-10-8
Molecular Formula	C18H27BO5
Molecular Weight	334.22 g/mol
Synonyms	4-(2-(1,3-Dioxolan-2-yl)ethoxy)phenylboronic acid pinacol ester; 2-[4-([1,3]Dioxolan-2-ylmethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(2-(1,3-Dioxolan-2-yl)ethoxy)benzeneboronic acid pinacol ester; 4-(2-(1,3-Dioxolan-2-yl)ethoxy)phenylboronic acid, pinacol ester; 850411-10-8; [4-[2-(1,3-Dioxolan-2-yl)ethoxy]phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-[4-([1,3]Dioxolan-2-Ylmethoxy)-Phenyl]-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere (argon or nitrogen) to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.