Description

4-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxy]-Butyric Acid Ethyl Ester is a high-value, synthetically versatile boronic ester derivative, serving as a critical building block in modern organic synthesis. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precision and reliability in intermediate supply are paramount.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing biaryl and heterobiaryl scaffolds common in drug discovery.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific aromatic coupling steps.
• Material Science Research: Building block for developing organic electronic materials, such as polymers for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the creation of tagged molecules and probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs (Contract Research Organizations) and CMOs (Contract Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	4-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxy]-Butyric Acid Ethyl Ester
CAS No.	850411-09-5
Molecular Formula	C18H27BO5
Molecular Weight	334.22 g/mol
Synonyms	Ethyl 4-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]butyrate; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy Butyric Acid Ethyl Ester; 4-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)butanoic Acid Ethyl Ester; Ethyl 4-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)butanoate; Boric acid, B-[3-[4-(ethoxycarbonyl)butoxy]phenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our production of 4-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxy]-Butyric Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.