Description

2-[3-([1,3]Dioxolan-2-Ylmethoxy)-Phenyl]-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block in modern organic synthesis, enabling the formation of complex carbon-carbon bonds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures prevalent in drug discovery.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in research applications.
• Process Chemistry: Enables scalable, efficient routes for the commercial production of fine chemicals.

Basic Information

Product Name	2-[3-([1,3]Dioxolan-2-Ylmethoxy)-Phenyl]-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
CAS No.	850411-08-4
Molecular Formula	C₁₈H₂₇BO₅
Molecular Weight	334.22 g/mol
Synonyms	3-(2-(1,3-Dioxolan-2-yl)ethoxy)phenylboronic acid pinacol ester; 2-[3-(2-(1,3-Dioxolan-2-yl)ethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3-(2-(1,3-Dioxolan-2-yl)ethoxy)phenyl)boronic acid pinacol ester; 850411-08-4; Boronic acid, B-[3-[2-(1,3-dioxolan-2-yl)ethoxy]phenyl]-, pinanediol ester; PINACOL 3-(2-(1,3-DIOXOLAN-2-YL)ETHOXY)PHENYLBORONATE
EINECS	Contact for details

Quality Control

Every batch of our 2-[3-([1,3]Dioxolan-2-Ylmethoxy)-Phenyl]-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.