Description

[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxy]-Acetic Acid Ethyl Ester is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile and stable intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and material science applications.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific biaryl motifs.
• Material Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials and other functional organic electronic compounds.
• Ligand & Catalyst Preparation: Employed in the synthesis of sophisticated ligands for catalysis and molecular recognition applications.
• Chemical Biology & Probe Development: Utilized to create molecular probes and bioconjugates for diagnostic and research purposes.
• Academic & Industrial R&D: A fundamental reagent for method development and exploring new synthetic pathways in research laboratories.

Basic Information

Product Name	[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxy]-Acetic Acid Ethyl Ester
CAS No.	850411-07-3
Molecular Formula	C₁₆H₂₃BO₅
Molecular Weight	306.16 g/mol
Synonyms	Ethyl [3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]acetate; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxyacetic Acid Ethyl Ester; 2-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]acetic Acid Ethyl Ester; 850411-07-3; Ethyl 2-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]acetate; B-[3-(Ethoxycarbonylmethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Every batch of our [3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxy]-Acetic Acid Ethyl Ester undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive cross-coupling reactions. Our quality assurance protocols include advanced chromatographic and spectroscopic methods to verify identity, purity, and the absence of critical impurities like palladium catalysts. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment, ensuring full traceability and compliance with your internal quality systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.