Description

2-(2-Bromo-Phenyl)-1-(4-Pyridin-2-Yl-[1,4]Diazepan-1-Yl)-Ethanone is a high-purity, advanced pharmaceutical intermediate featuring a unique diazepane-pyridine scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting G-protein-coupled receptors (GPCRs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile diazepane core.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds and probes to study biological pathways and protein functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of complex molecules for client projects.
• Library Synthesis: Used to create focused chemical libraries for high-throughput screening (HTS) in drug discovery campaigns.

Basic Information

Product Name	2-(2-Bromo-Phenyl)-1-(4-Pyridin-2-Yl-[1,4]Diazepan-1-Yl)-Ethanone
CAS No.	850349-16-5
Molecular Formula	C18H20BrN3O
Molecular Weight	374.28 g/mol
Synonyms	1-[4-(2-Pyridinyl)-1,4-diazepan-1-yl]-2-(2-bromophenyl)ethanone; 2-(2-Bromophenyl)-1-[4-(pyridin-2-yl)-1,4-diazepan-1-yl]ethanone; Ethanone, 1-[4-(2-pyridinyl)-1,4-diazepan-1-yl]-2-(2-bromophenyl)-; 850349-16-5; 2-(2-Bromophenyl)-1-(4-(pyridin-2-yl)-1,4-diazepan-1-yl)ethanone; 1-(4-(Pyridin-2-yl)-1,4-diazepan-1-yl)-2-(2-bromophenyl)ethanone
EINECS	Contact for details

Quality Control

Our 2-(2-Bromo-Phenyl)-1-(4-Pyridin-2-Yl-[1,4]Diazepan-1-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.