Description

[Rh Cod (R)-Phanephos]Bf4 is a high-purity, chiral organometallic catalyst complex, specifically a rhodium(I) complex with (R)-Phanephos as the chiral ligand and tetrafluoroborate as the counterion. This compound is critically important for enabling highly enantioselective hydrogenation and other asymmetric transformations in fine chemical and pharmaceutical synthesis. It is an essential tool for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries who require precise stereochemical control to produce single-enantiomer intermediates and active ingredients.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Key catalyst in the production of enantiomerically pure active pharmaceutical ingredients (APIs), such as β-amino acids and chiral drug candidates.
• Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Enables the synthesis of high-value chiral building blocks and specialty chemicals for flavors, fragrances, and electronic materials.
• Academic and Industrial R&D: A valuable reference catalyst for method development and studying asymmetric catalytic mechanisms.
• Process Chemistry Optimization: Employed in scaling up enantioselective reactions from laboratory to pilot plant and commercial production.

Basic Information

Product Name	[Rh Cod (R)-Phanephos]Bf4
CAS No.	849950-56-7
Molecular Formula	C44H44BF4O2P2Rh
Molecular Weight	852.47 g/mol
Synonyms	(1,5-Cyclooctadiene)((R)-(-)-1,2-Bis(diphenylphosphino)-1,1'-binaphthyl)rhodium(I) Tetrafluoroborate; Rh(COD)((R)-Phanephos)BF4; Rhodium(I)-(R)-Phanephos-COD Tetrafluoroborate; (R)-Phanephos Rhodium Cyclooctadiene Tetrafluoroborate; (R)-(-)-1,2-Bis(diphenylphosphino)-1,1'-binaphthyl(1,5-cyclooctadiene)rhodium(I) Tetrafluoroborate; Rh-(R)-BINAP-Type Catalyst Complex
EINECS	Contact for details

Quality Control

Our [Rh Cod (R)-Phanephos]Bf4 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for chiral purity and assay, NMR for structural confirmation, and ICP-MS for heavy metal content, to ensure it meets the high standards required for catalytic applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (argon or nitrogen) for long-term stability. The material is light-sensitive and should be handled in a glovebox or under an inert atmosphere to prevent decomposition.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Rhodium Content (ICP)	11.8 - 12.2%
Solubility	Soluble in dichloromethane, toluene; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.