Description

Methyl 2-(2-Chloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetate is a high-purity, advanced pharmaceutical intermediate featuring a boronic ester functional group. This compound is critical for enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental to modern medicinal chemistry and drug discovery. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronate ester coupling partner for the formation of carbon-carbon bonds under mild conditions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-boronate structures.
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology & Probe Development: Utilized for creating molecular probes and labeled compounds for biochemical assays and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	Methyl 2-(2-Chloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetate
CAS No.	849934-95-8
Molecular Formula	C15H20BClO4
Molecular Weight	310.58 g/mol
Synonyms	2-(2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetic acid methyl ester; Methyl (2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate; 2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzeneacetic acid methyl ester; Pinacol (2-Chloro-4-(methoxycarbonylmethyl)phenyl)boronate; Boronic acid, B-[2-chloro-4-[(methoxycarbonyl)methyl]phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-(2-Chloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee batch-to-batch consistency and support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.