Description

Methyl 2-Amino-4-((tert-Butoxycarbonyl)Amino)Benzoate is a high-purity, protected amino acid derivative primarily used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular architecture, particularly in the development of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). Its primary value lies in providing a reactive amine group protected by a Boc (tert-butoxycarbonyl) group, which is stable under a wide range of reaction conditions and can be selectively deprotected. Key industries that rely on this intermediate include pharmaceutical R&D, agrochemical synthesis, and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for compounds containing ortho-aminobenzoate scaffolds.
• Peptidomimetic Synthesis: Used in the construction of peptide analogs and mimetics where the protected amino group is crucial for sequential coupling reactions.
• Agrochemical Active Ingredient Development: Serves as a building block for creating new herbicides, fungicides, and insecticides with specific activity profiles.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for metal catalysis and organocatalysts.
• Fluorescent Dye and Sensor Chemistry: Acts as a starting material for synthesizing advanced organic dyes and molecular sensors due to its aromatic amine structure.
• Polymer and Material Science: Used to introduce functional aromatic amine groups into polymer backbones for specialty materials.

Basic Information

Item	Detail
Product Name	Methyl 2-Amino-4-((tert-Butoxycarbonyl)Amino)Benzoate
CAS No.	849792-91-2
Molecular Formula	C13H18N2O4
Molecular Weight	266.29 g/mol
Synonyms	Methyl 2-Amino-4-(Boc-amino)benzoate; 2-Amino-4-[(tert-butoxycarbonyl)amino]benzoic acid methyl ester; Methyl 4-((tert-butoxycarbonyl)amino)-2-aminobenzoate; Boc-4-A-DL-Phe-OMe (related derivative); 4-(Boc-amino)anthranilic acid methyl ester; Methyl 2-amino-4-[(2-methylpropan-2-yl)oxycarbonylamino]benzoate; 2-Amino-4-[(tert-butoxycarbonyl)amino]methyl benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Amino-4-((tert-Butoxycarbonyl)Amino)Benzoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials undergo rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, and we can accommodate specific customer testing requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.