Description

Phthalic Anhydride-4-Boronic Acid Pinacol Ester is a high-value, multifunctional aromatic boronic ester derivative. This compound matters as a critical synthetic intermediate, offering a protected boronic acid functionality and a reactive anhydride group for sequential chemical modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing complex molecules, particularly in Suzuki-Miyaura cross-coupling reactions and polymer synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates via cross-coupling chemistry.
• Polymer & Material Science: Monomer for creating novel polyimides, polyesters, and other specialty polymers with tailored thermal and mechanical properties.
• Ligand & Catalyst Development: Precursor for synthesizing sophisticated ligands used in homogeneous catalysis and organometallic chemistry.
• Organic Synthesis: Versatile reagent for introducing phthalic anhydride and boronic acid moieties into target molecules in a controlled manner.
• Chemical Research: Valuable tool for methodological development in academic and industrial R&D laboratories.
• Sensor & Diagnostic Agent Synthesis: Intermediate in the production of molecular probes and diagnostic components.

Basic Information

Product Name	Phthalic Anhydride-4-Boronic Acid Pinacol Ester
CAS No.	849677-21-0
Molecular Formula	C16H19BO5
Molecular Weight	302.13 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phthalic anhydride; 1,3-Dioxo-1,3-dihydro-2-benzofuran-5-boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isobenzofuran-1,3-dione; Phthalic Anhydride-4-Boronate Pinacol Ester; 4-BPin-Phthalic Anhydride; 4-(BPin)Phthalic Anhydride; 5-BPin-isobenzofuran-1,3-dione
EINECS	Contact for details

Quality Control

Our Phthalic Anhydride-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.