Description

3,3-Difluorocyclohexanecarboxylic Acid is a versatile fluorinated building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity and physicochemical properties imparted by the difluoro-substituted cyclohexane ring, which is crucial for modulating the biological activity and metabolic stability of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, metabolic diseases, and inflammation.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance lipophilicity, membrane permeability, and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or metal-organic frameworks (MOFs) used in asymmetric catalysis and separation sciences.
• Material Science Research: Employed in the synthesis of fluorinated polymers or liquid crystals, where it can influence thermal stability, dielectric properties, and optical characteristics.
• Chemical Biology Probe: Useful for incorporating fluorinated motifs into bioactive probes to study protein-ligand interactions and metabolic pathways via techniques like 19F NMR.

Basic Information

Product Name	3,3-Difluorocyclohexanecarboxylic Acid
CAS No.	849669-20-1
Molecular Formula	C7H10F2O2
Molecular Weight	164.15 g/mol
Synonyms	3,3-Difluorocyclohexane-1-carboxylic Acid; Cyclohexanecarboxylic acid, 3,3-difluoro-; 3,3-Difluorocyclohexanecarboxylate; 849669-20-1; 3,3-Difluoro-cyclohexanecarboxylic acid; 3,3-Difluorocyclohexane carboxylic acid
EINECS	Contact for details

Quality Control

Our 3,3-Difluorocyclohexanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and heat sources. Due to its acidic nature, ensure containers are made of compatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.