Description

1-(4-Bromophenyl)-3-(Dimethylamino)Prop-2-En-1-One is a high-purity, versatile chemical building block featuring a brominated aromatic ketone core functionalized with a dimethylamino enone group. This molecular structure makes it a valuable intermediate for synthesizing complex organic compounds, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought after by R&D chemists and process development scientists in the life sciences and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic system for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Dye & Pigment Synthesis: Acts as an intermediate for creating complex chromophores and functional dyes due to its conjugated enone system.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis, including cross-coupling and cyclization reactions.
• Chemical Biology: Utilized as a probe or labeling agent precursor in biochemical assay development and proteomics research.

Basic Information

Product Name	1-(4-Bromophenyl)-3-(Dimethylamino)Prop-2-En-1-One
CAS No.	849619-11-0
Molecular Formula	C11H12BrNO
Molecular Weight	254.13 g/mol
Synonyms	4'-Bromochalcone dimethylamino derivative; 3-(Dimethylamino)-1-(4-bromophenyl)-2-propen-1-one; 1-(4-Bromophenyl)-3-(dimethylamino)-2-propen-1-one; (E)-1-(4-Bromophenyl)-3-(dimethylamino)prop-2-en-1-one; 4-Bromo-β-dimethylaminopropiophenone; N,N-Dimethyl-3-(4-bromobenzoyl)allylamine; 849619-11-0; p-Bromophenyl dimethylamino vinyl ketone
EINECS	Contact for details

Quality Control

Our 1-(4-Bromophenyl)-3-(Dimethylamino)Prop-2-En-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a Certificate of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and stored away from direct light and moisture sources to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.