Description

Benzoic Acid, 2-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)-, Methyl Ester is a high-purity, specialty organoboron reagent featuring a protected boronic ester functional group. This compound is a critical building block in modern synthetic chemistry, enabling precise carbon-carbon bond formation through cross-coupling reactions. It is primarily utilized by pharmaceutical, agrochemical, and advanced materials research and development teams for the synthesis of complex molecules and novel chemical entities.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and other carbon-carbon bonds in pharmaceutical intermediates and active ingredients.
• Pharmaceutical Research & Development: Serves as a versatile building block for creating novel drug candidates and complex organic scaffolds.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides requiring specific boron-containing intermediates.
• Material Science: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Proteomics: Acts as a probe or linker molecule in bioconjugation and activity-based protein profiling studies.
• Academic & Industrial Research: A valuable tool for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	Benzoic Acid, 2-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)-, Methyl Ester
CAS No.	849412-52-8
Molecular Formula	C14H19BO4
Molecular Weight	262.11 g/mol
Synonyms	2-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzoic acid methyl ester; Methyl 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate; 2-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)methyl benzoate; Benzoic acid, 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-, methyl ester; Pinacol ester of 2-(Methoxycarbonyl)phenylboronic acid; 2-Methoxycarbonylphenylboronic acid pinacol ester; (2-(Methoxycarbonyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 2-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and structural integrity suitable for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the boronic ester group.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.