Description

5,5-Dimethyl-2-(2-Nitrophenyl)-1,3,2-Dioxaborinane is a specialized organoboron compound that serves as a valuable synthetic intermediate. Its core value lies in its role as a protected boronic acid derivative, offering enhanced stability for handling and storage compared to its free acid form. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for advanced synthesis, particularly in Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex aryl coupling.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as polymers and small molecules for OLEDs or OFETs.
• Ligand and Catalyst Development: Employed in the preparation of novel boron-containing ligands and catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes.
• Academic & Contract Research: Essential reagent for methodology development and complex molecule construction in academic and industrial R&D laboratories.

Basic Information

Product Name	5,5-Dimethyl-2-(2-Nitrophenyl)-1,3,2-Dioxaborinane
CAS No.	849412-51-7
Molecular Formula	C12H16BNO4
Molecular Weight	249.08 g/mol
Synonyms	2-(2-Nitrophenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 5,5-Dimethyl-2-(o-nitrophenyl)-1,3,2-dioxaborinane; (2-Nitrophenyl)-5,5-dimethyl-1,3,2-dioxaborinane; o-Nitrophenylboronic acid 5,5-dimethyl-1,3,2-dioxaborinane ester; 2-Nitrophenylboronic acid cyclic ester with neopentyl glycol; Boronic acid, (2-nitrophenyl)-, cyclic ester with 2,2-dimethyl-1,3-propanediol
EINECS	Contact for details

Quality Control

Our 5,5-Dimethyl-2-(2-Nitrophenyl)-1,3,2-Dioxaborinane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent in-house specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.