Description

1-Methyl-1H-Imidazole-5-Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters as a key reagent in cross-coupling reactions, enabling the efficient construction of complex heterocyclic molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A pivotal reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and this boronic acid derivative.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of novel drug candidates, particularly those containing imidazole-based scaffolds.
• Agrochemical Development: Serves as a building block for creating new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Employed in the synthesis of organic electronic materials, ligands for catalysis, and advanced polymers.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biological studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized imidazole cores.

Basic Information

Product Name	1-Methyl-1H-Imidazole-5-Boronic Acid
CAS No.	849062-28-8
Molecular Formula	C4H7BN2O2
Molecular Weight	125.93 g/mol
Synonyms	5-Borono-1-methyl-1H-imidazole; 1-Methyl-5-imidazoleboronic Acid; 1-Methyl-1H-imidazol-5-ylboronic Acid; (1-Methyl-1H-imidazol-5-yl)boronic Acid; 1-Methylimidazole-5-boronic Acid; 1-Methyl-1H-imidazole-5-boronic Acid Pinacol Ester (common derivative); 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-1H-imidazole
EINECS	Contact for details

Quality Control

Our 1-Methyl-1H-Imidazole-5-Boronic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Assay (NMR)	≥95%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.