Description

3-Chloro-4-(3'-Bromobenzyloxy)Phenylboronic Acid is a high-purity, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual halogenated benzyloxy structure, which provides unique reactivity and selectivity for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging its halogenated aromatic system for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in palladium-catalyzed cross-coupling reactions to form biaryl bonds.
• Ligand Synthesis: Utilized for the preparation of sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Diagnostic Reagents: Potential use in the development of biochemical probes and sensors due to its boronic acid functionality's affinity for diols.

Basic Information

Product Name	3-Chloro-4-(3'-Bromobenzyloxy)Phenylboronic Acid
CAS No.	849062-25-5
Molecular Formula	C13H11BBrClO3
Molecular Weight	340.39 g/mol
Synonyms	[3-Chloro-4-[(3-bromophenyl)methoxy]phenyl]boronic acid; (3-Chloro-4-((3-bromobenzyl)oxy)phenyl)boronic acid; 3-Chloro-4-(3-bromobenzyloxy)benzeneboronic acid; 4-(3-Bromobenzyloxy)-3-chlorophenylboronic acid; B-[3-Chloro-4-[(3-bromophenyl)methoxy]phenyl]boronic acid; 849062-25-5; AKOS025310065; AS-80511
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-4-(3'-Bromobenzyloxy)Phenylboronic Acid undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for advanced synthetic applications. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and IR spectroscopy, is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.