Description

trans-2-Cyclopropylvinylboronic Acid Pinacol Ester, 96% CAS NO 849061-99-0 is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound is a critical reagent in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between the vinylboronate and aryl or vinyl halides/triflates.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing cyclopropyl and vinyl motifs.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and insecticides with tailored biological activity.
• Material Science: Serves as a precursor for creating functionalized polymers or organic electronic materials.
• Medicinal Chemistry: Facilitates the exploration of structure-activity relationships (SAR) by introducing the cyclopropylvinyl moiety into lead compounds.
• Chemical Biology: Can be used to create probes or labeled compounds for studying biological processes.

Basic Information

Product Name	trans-2-Cyclopropylvinylboronic Acid Pinacol Ester
CAS No.	849061-99-0
Molecular Formula	C11H19BO2
Molecular Weight	194.08 g/mol
Synonyms	trans-2-Cyclopropylethylene-1-boronic Acid Pinacol Ester; (E)-2-Cyclopropylvinylboronic Acid Pinacol Ester; trans-2-Cyclopropylvinylboronic Acid Neopentyl Glycol Ester (common alternative); B-(trans-2-Cyclopropylethylenyl)boronic Acid Pinacol Ester; Cyclopropylvinyl Pinacol Boronate; (E)-2-Cyclopropylethyl-1-boronic Acid Pinacol Ester; 849061-99-0; trans-2-Cyclopropylvinyl-Bpin
EINECS	Contact for details

Quality Control

Our trans-2-Cyclopropylvinylboronic Acid Pinacol Ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high chemical purity. Every lot undergoes comprehensive analytical testing, including NMR and HPLC, to verify identity, purity, and the absence of critical impurities. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 96%
Isomeric Purity (trans/cis ratio)	≥ 98:2 (by GC or HPLC)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.