Description

Ethyl 4-Fluoro-4-Methyl-2-Pent-4-Enamidopentanoate is a specialized fluorinated organic building block of significant interest in advanced synthetic chemistry. Its molecular architecture, featuring both a fluoro-substituted quaternary carbon and an enamide ester, makes it a valuable precursor for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in creating advanced intermediates for novel pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental persistence.
• Advanced Material Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and coatings with unique surface properties.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for studying biological mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Ethyl 4-Fluoro-4-Methyl-2-Pent-4-Enamidopentanoate
CAS No.	848949-92-8
Molecular Formula	C13H20FNO3
Molecular Weight	257.30 g/mol
Synonyms	Ethyl 4-fluoro-4-methyl-2-(pent-4-enamido)pentanoate; 4-Fluoro-4-methyl-2-(4-pentenamido)pentanoic Acid Ethyl Ester; 848949-92-8; 4-Fluoro-4-methyl-2-pent-4-enamidopentanoic acid ethyl ester; Ethyl (2R/S)-4-fluoro-4-methyl-2-(pent-4-enamido)pentanoate (racemic); Pentanoic acid, 4-fluoro-4-methyl-2-(4-pentenamido)-, ethyl ester; A fluorinated enamide ester intermediate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Fluoro-4-Methyl-2-Pent-4-Enamidopentanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.