Description

1H-Indole-1-Carboxylic Acid, 5-Acetyl-2-Borono-, 1-(1,1-Dimethylethyl) Ester (9Ci) is a specialized boronic acid ester derivative of indole, serving as a high-value synthetic intermediate. This compound matters for its role in facilitating complex organic transformations, particularly in the synthesis of novel pharmaceutical candidates and advanced materials. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing intricate molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Suzuki-Miyaura Cross-Coupling Reactions: The boronic ester functional group makes it a crucial reagent for forming carbon-carbon bonds in medicinal chemistry and material science.
• Agrochemical Research: Used in the development of new active ingredients for crop protection and plant growth regulation.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for synthesizing complex organic molecules used in electronic and optoelectronic devices.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and enzyme functions.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 5-Acetyl-2-Borono-, 1-(1,1-Dimethylethyl) Ester (9Ci)
CAS No.	848357-29-9
Molecular Formula	C15H18BNO4
Molecular Weight	287.12 g/mol
Synonyms	5-Acetyl-2-borono-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl 5-acetyl-2-borono-1H-indole-1-carboxylate; 5-Acetyl-1-Boc-indole-2-boronic acid pinacol ester (common misnomer check); 1-Boc-5-acetylindole-2-boronic acid pinacol ester; 2-Borono-5-acetyl-1H-indole-1-carboxylic acid tert-butyl ester; 848357-29-9; tert-Butyl 5-acetyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate (likely pinacol ester variant).
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Carboxylic Acid, 5-Acetyl-2-Borono-, 1-(1,1-Dimethylethyl) Ester (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.