Description

2-Cyclopropylmethoxy-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine is a high-value, functionalized pyridine boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in creating complex heterocyclic cores found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific pyridine-based structures.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysts, and advanced polymers.
• Cross-Coupling Reactions: Primarily utilized in Suzuki-Miyaura coupling to form carbon-carbon bonds, a cornerstone methodology in medicinal and process chemistry.
• Chemical Biology Probes: Serves as a precursor for creating labeled compounds and probes used in biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Item	Details
Product Name	2-Cyclopropylmethoxy-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine
CAS No.	848243-26-5
Molecular Formula	C15H22BNO3
Molecular Weight	275.15 g/mol
Synonyms	2-(Cyclopropylmethoxy)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Boronic acid, 2-(cyclopropylmethoxy)pyridine-, 1,3,2-dioxaborolane ester; 2-Cyclopropylmethoxy-3-pyridineboronic acid pinacol ester; 2-(Cyclopropylmethoxy)pyridine-3-boronic acid pinacol ester; Pyridine, 2-(cyclopropylmethoxy)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 848243-26-5; 2-CPME-3-BPin-Pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Cyclopropylmethoxy-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.