Description

2-Oxabicyclo[2.2.2]Oct-7-Ene-5-Carboxylicacid,7-Fluoro-3-Oxo-,Methylester,(1R,4S,5S)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic lactone derivative, identified by CAS number 847823-77-2. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile chiral building block for complex organic synthesis. It is primarily required by R&D and production teams in the pharmaceutical and fine chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Asymmetric Synthesis: Utilized as a building block in catalytic asymmetric reactions to introduce specific stereocenters with high enantiomeric purity.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and route scouting for API manufacturing.
• Fine Chemical Production: Used in the custom synthesis of specialty chemicals, agrochemicals, and high-value materials requiring its unique bicyclic framework.

Basic Information

Item	Details
Product Name	2-Oxabicyclo[2.2.2]Oct-7-Ene-5-Carboxylicacid,7-Fluoro-3-Oxo-,Methylester,(1R,4S,5S)-Rel-(9Ci)
CAS No.	847823-77-2
Molecular Formula	C9H9FO4
Molecular Weight	200.16 g/mol
Synonyms	(1R,4S,5S)-rel-7-Fluoro-3-oxo-2-oxabicyclo[2.2.2]oct-7-ene-5-carboxylic acid methyl ester; Methyl (1R,4S,5S)-rel-7-fluoro-3-oxo-2-oxabicyclo[2.2.2]oct-7-ene-5-carboxylate; 7-Fluoro-3-oxo-2-oxabicyclo[2.2.2]oct-7-ene-5-carboxylic acid methyl ester, (1R,4S,5S)-rel-; Bicyclic fluorolactone ester; Fluorinated oxabicyclo[2.2.2]octene derivative
EINECS	Contact for details

Quality Control

Our 2-Oxabicyclo[2.2.2]Oct-7-Ene-5-Carboxylicacid,7-Fluoro-3-Oxo-,Methylester,(1R,4S,5S)-Rel-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.