Description

3-Methyl-1-Propyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is a high-value, functionalized pyrazole boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyrazole or complex aryl-heterocycle motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific heterocyclic structures for bioactivity.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular architecture is crucial.
• Suzuki-Miyaura Cross-Coupling: Acts as a stable, air-handleable boronate ester reagent for palladium-catalyzed carbon-carbon bond formation with various aryl/heteroaryl halides.
• Chemical Biology & Probe Development: Utilized to create tagged molecules and bioconjugates for studying biological processes and target engagement.
• Catalyst & Ligand Development: Serves as a precursor for synthesizing novel N-heterocyclic carbene (NHC) ligands or metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	3-Methyl-1-Propyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole
CAS No.	847818-80-8
Molecular Formula	C13H23BN2O2
Molecular Weight	250.15 g/mol
Synonyms	1-Propyl-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 3-Methyl-1-propyl-1H-pyrazole-5-boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methyl-1-propyl-1H-pyrazole; 1H-Pyrazole-5-boronic acid, 3-methyl-1-propyl-, pinacol ester; Pyrazole boronic ester, 3-methyl-1-propyl-; 847818-80-8; (3-Methyl-1-propyl-1H-pyrazol-5-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Methyl-1-Propyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.