Description

1,3-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is a high-value, heterocyclic boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for drug discovery, catalyst development, and functional polymer synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for constructing pyrazole-containing heterocycles.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific pyrazole-boronate motifs.
• Material Science: Building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Catalyst & Ligand Development: Serves as a precursor for synthesizing novel metal-organic frameworks (MOFs) and specialized ligands for catalysis.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new carbon-carbon bond-forming reactions and library synthesis.
• Custom Synthesis: Employed by fine chemical manufacturers for the contract production of bespoke, complex organic molecules.

Basic Information

Product Name	1,3-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole
CAS No.	847818-79-5
Molecular Formula	C11H19BN2O2
Molecular Weight	222.10 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dimethyl-1H-pyrazole; 1,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole; 1,3-Dimethyl-5-(pinacolatoboryl)pyrazole; 1H-Pyrazole, 1,3-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(Pinacolatoboryl)-1,3-dimethylpyrazole; 1,3-Dimethyl-5-pyrazoleboronic acid pinacol ester; 847818-79-5
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.