Description

1-Propyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)-1H-indazole is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and the development of functional organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and central nervous system (CNS) research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling.
• Material Science: Precursor for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Bioconjugation: Utilized in probe and linker synthesis for labeling biomolecules and studying biological processes.
• Academic & Industrial R&D: A fundamental reagent for methodological development and complex molecule synthesis in research laboratories.

Basic Information

Product Name	1-Propyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)-1H-indazole
CAS No.	847818-76-2
Molecular Formula	C₁₆H₂₃BN₂O₂
Molecular Weight	286.18 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-propyl-1H-indazole; 1-Propyl-1H-indazole-5-boronic acid pinacol ester; 1-Propyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 1-Propyl-5-indazoleboronic acid pinacol ester; 847818-76-2; 1H-Indazole, 1-propyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 1-Propyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)-1H-indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B) and HPLC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO standards for pharmaceutical and industrial applications, ensuring reliable supply chain integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	≥95.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.