Description

1-(2-Methoxyethyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecules. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for diagnostic and research applications.
• Cross-Coupling Reactions: A specialized reagent for palladium-catalyzed Suzuki-Miyaura couplings, facilitating carbon-carbon bond formation under mild conditions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs serving the life sciences industry.

Basic Information

Product Name	1-(2-Methoxyethyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole
CAS No.	847818-71-7
Molecular Formula	C₁₂H₂₁BN₂O₃
Molecular Weight	252.12 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-methoxyethyl)-1H-pyrazole; 1-(2-Methoxyethyl)-1H-pyrazole-4-boronic acid pinacol ester; 1-(2-Methoxyethyl)pyrazole-4-boronic acid pinacol ester; 1H-Pyrazole-4-boronic acid, 1-(2-methoxyethyl)-, 1,3,2-dioxaborolane ester; Pyrazole boronic ester derivative; Suzuki coupling reagent; Boronate ester intermediate.
EINECS	Contact for details

Quality Control

Our 1-(2-Methoxyethyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for each lot, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.