Description

2-Isobutyl-2H-Pyrazole-3-Boronic Acid is a specialized organoboron building block crucial for modern synthetic chemistry. This compound matters as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in creating pyrazole-containing molecules with potential therapeutic activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific heterocyclic structures.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysis, and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid partner for palladium-catalyzed carbon-carbon bond formation with aryl or vinyl halides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme functions.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in chemistry laboratories worldwide.

Basic Information

Item	Detail
Product Name	2-Isobutyl-2H-Pyrazole-3-Boronic Acid
CAS No.	847818-64-8
Molecular Formula	C7H13BN2O2
Molecular Weight	168.00 g/mol
Synonyms	2-(2-Methylpropyl)-2H-pyrazole-3-boronic acid; 2-Isobutyl-1H-pyrazole-3-boronic acid; 3-Borono-2-isobutyl-2H-pyrazole; 2-Isobutyl-2H-pyrazol-3-ylboronic acid; Pyrazole-3-boronic acid, 2-isobutyl- derivative; SCHEMBL21806227; BDBM50389375; AKOS005258155
EINECS	Contact for details

Quality Control

Our 2-Isobutyl-2H-Pyrazole-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and oxidation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.