Description

1-Propyl-1H-Pyrazol-4-Ylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to synthesize novel, complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyrazole heterocycles.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for the palladium-catalyzed formation of biaryl and heteroaryl bonds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with pyrazole-based structures.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, ligands for catalysts, and emissive materials for organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Useful for creating molecular probes and bioconjugates for studying biological systems.
• Library Synthesis for High-Throughput Screening: Facilitates the rapid generation of diverse compound libraries in drug discovery programs.

Basic Information

Product Name	1-Propyl-1H-Pyrazol-4-Ylboronic Acid
CAS No.	847818-57-9
Molecular Formula	C6H11BN2O2
Molecular Weight	154.98 g/mol
Synonyms	4-(1-Propyl-1H-pyrazol-4-yl)boronic acid; 1-Propyl-1H-pyrazole-4-boronic acid; 1-Propyl-4-pyrazoleboronic acid; (1-Propyl-1H-pyrazol-4-yl)boronic acid; 1-n-Propyl-1H-pyrazole-4-boronic acid; 1-Propylpyrazole-4-boronic acid; B-(1-Propyl-1H-pyrazol-4-yl)boronic acid
EINECS	Contact for details

Quality Control

Our 1-Propyl-1H-Pyrazol-4-Ylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.