Description

3-(2-Chloro-5-Fluoro-Phenyl)-Propionic Acid is a high-purity fluorinated aromatic propionic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both chloro and fluoro substituents to modulate reactivity, lipophilicity, and metabolic stability in target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to construct complex active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials for displays and lighting applications.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring new chemical entities.
• Custom Synthesis & Contract Manufacturing: A starting material for specialty chemical manufacturers offering bespoke synthesis services to client specifications.

Basic Information

Product Name	3-(2-Chloro-5-Fluoro-Phenyl)-Propionic Acid
CAS No.	847492-00-6
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	2-Chloro-5-fluorobenzene propanoic acid; 3-(2-Chloro-5-fluorophenyl)propanoic acid; 2-Chloro-5-fluoro-β-phenylpropionic acid; (2-Chloro-5-fluorophenyl)propionic acid; 847492-00-6; 3-(2-Chloro-5-fluorophenyl)propionic acid; 2-Chloro-5-fluorohydrocinnamic acid
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Chloro-5-Fluoro-Phenyl)-Propionic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.