Description

4-(n-Methylamino)Phenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound matters as a critical building block in cross-coupling reactions, offering enhanced stability and reactivity for constructing complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the formation of carbon-carbon bonds in the synthesis of biaryl compounds.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and activity-based protein profiling (ABPP) reagents.
• Library Synthesis for Drug Discovery: Enables high-throughput parallel synthesis of diverse compound libraries for screening.

Basic Information

Product Name	4-(n-Methylamino)Phenylboronic Acid, Pinacol Ester
CAS No.	845870-55-5
Molecular Formula	C14H22BNO2
Molecular Weight	247.14 g/mol
Synonyms	4-(Methylamino)benzeneboronic acid pinacol ester; N-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; [4-(Methylamino)phenyl]boronic acid pinacol ester; 2-[4-(Methylamino)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(N-Methylamino)phenylboronic acid pinacol ester; Pinacol [4-(methylamino)phenyl]boronate; B-[4-(Methylamino)phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-(n-Methylamino)Phenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for prolonged manipulations to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.