Description

4'-(3,4-Difluorophenoxy)Acetophenone is a high-purity organic intermediate featuring a difluorophenoxy-substituted acetophenone core structure. This compound is valued for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical active ingredients. It is primarily sought by research institutions and manufacturers in the life sciences sector for developing new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides and fungicides, leveraging the bioactivity of the difluorophenoxy moiety.
• Material Science Research: Used in the synthesis of specialty polymers and liquid crystals, where the fluorine atoms impart desirable thermal and chemical stability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and other advanced organic transformations to construct complex molecular architectures in academic and industrial R&D.

Basic Information

Product Name	4'-(3,4-Difluorophenoxy)Acetophenone
CAS No.	845866-50-4
Molecular Formula	C14H10F2O2
Molecular Weight	248.23 g/mol
Synonyms	1-[4-(3,4-Difluorophenoxy)phenyl]ethanone; 4-(3,4-Difluorophenoxy)acetophenone; 4-Acetyl-3',4'-difluorodiphenyl ether; 3',4'-Difluoro-4-acetyldiphenyl ether; 4-Acetylphenyl 3,4-difluorophenyl ether; Ethanone, 1-[4-(3,4-difluorophenoxy)phenyl]-; 845866-50-4
EINECS	Contact for details

Quality Control

Our 4'-(3,4-Difluorophenoxy)Acetophenone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.