Description

2'-(3-Fluorobenzyloxy)Acetophenone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents and agrochemicals, where the introduction of fluorine atoms is a critical strategy for modulating biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries engaged in creating new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting the central nervous system, inflammation, and oncology.
• Agrochemical Research: Serves as a key precursor in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine moiety for enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Employed in the synthesis of advanced organic materials, including liquid crystals and organic semiconductors, where its specific aromatic and fluorinated structure imparts desired electronic properties.
• Chemical Biology Probe Synthesis: Utilized to create fluorinated analogs of bioactive molecules for studying metabolic pathways and protein-ligand interactions.

Basic Information

Product Name	2'-(3-Fluorobenzyloxy)Acetophenone
CAS No.	845823-26-9
Molecular Formula	C15H13FO2
Molecular Weight	244.26 g/mol
Synonyms	1-[2-[(3-Fluorophenyl)methoxy]phenyl]ethanone; 2'-Hydroxyacetophenone 3-fluorobenzyl ether; 2-Acetylphenyl 3-fluorobenzyl ether; 3-Fluorobenzyl 2-acetylphenyl ether; 2-(3-Fluorobenzyloxy)acetophenone; α-Methyl-2-[(3-fluorobenzyl)oxy]benzyl alcohol (keto form)
EINECS	Contact for details

Quality Control

Our 2'-(3-Fluorobenzyloxy)Acetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.