Description

2'-iso-Propyl-2,2,2-Trifluoroacetophenone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the trifluoroacetyl group and the isopropyl-substituted aromatic ring, making it a critical intermediate for constructing complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethylated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine atoms contribute to improved efficacy and environmental profile.
• Ligand and Catalyst Precursor: Serves as a starting material for the synthesis of specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of fluorinated organic compounds for advanced materials, such as liquid crystals or polymers with specific optical or electronic properties.
• Custom Synthesis and Contract Manufacturing: A valuable building block for fine chemical companies offering bespoke synthesis services to clients in life sciences.

Basic Information

Product Name	2'-iso-Propyl-2,2,2-Trifluoroacetophenone
CAS No.	845823-14-5
Molecular Formula	C11H11F3O
Molecular Weight	216.20 g/mol
Synonyms	1-(2-Isopropylphenyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(2-propan-2-ylphenyl)ethanone; 2-Isopropyl-α,α,α-trifluoroacetophenone; α,α,α-Trifluoro-2'-isopropylacetophenone; 2'-iso-Propyl-α,α,α-trifluoroacetophenone; 2-(Trifluoroacetyl)cumene
EINECS	Contact for details

Quality Control

Our 2'-iso-Propyl-2,2,2-Trifluoroacetophenone is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance in cGMP and ISO 9001 environments for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.