Description

5-(4-tert-Butylphenyl)-3-Methyl-5-Oxovaleric Acid is a high-value organic intermediate characterized by its ketovaleric acid structure with a bulky tert-butylphenyl substituent. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical compounds and specialty chemicals, offering precise molecular architecture for downstream functionalization. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced material sectors seeking to develop new active ingredients or functional polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex, lipophilic carboxylic acid derivatives.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and plant growth regulators, leveraging its aromatic and aliphatic acid functionality.
• Liquid Crystal & OLED Material Research: Used in the synthesis of organic semiconductors and liquid crystal compounds, where the tert-butylphenyl group influences mesomorphic and electronic properties.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polyesters and polyamides with enhanced thermal stability and specific solubility profiles.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex molecules via reactions at the ketone and carboxylic acid functional groups.
• Fine Chemical Production: Integral to the multi-step synthesis of dyes, pigments, and performance chemicals requiring specific aromatic-aliphatic hybrid structures.

Basic Information

Product Name	5-(4-tert-Butylphenyl)-3-Methyl-5-Oxovaleric Acid
CAS No.	845781-47-7
Molecular Formula	C16H22O3
Molecular Weight	262.35 g/mol
Synonyms	3-Methyl-5-oxo-5-[4-(tert-butyl)phenyl]pentanoic Acid; 5-[4-(1,1-Dimethylethyl)phenyl]-3-methyl-5-oxopentanoic Acid; 5-(4-tert-Butylbenzoyl)-3-methylvaleric Acid; 4-(4-tert-Butylphenyl)-4-oxo-2-methylbutanoic Acid (tautomeric form); 5-(p-tert-Butylphenyl)-3-methyl-5-oxovaleric Acid; 5-Oxo-5-(4-tert-butylphenyl)-3-methylpentanoic Acid; 3-Methyl-5-(4-tert-butylphenyl)-5-oxopentanoic Acid; 5-(4-tert-Butylphenyl)-3-methyllevulinic Acid
EINECS	Contact for details

Quality Control

Our 5-(4-tert-Butylphenyl)-3-Methyl-5-Oxovaleric Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in pharmaceutical and high-purity applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.