Description

2-(3,4-Difluorophenyl)-1-Phenylethanone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and novel agrochemicals where the introduction of a difluorophenyl moiety is crucial for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorine atoms enhance metabolic stability and bioavailability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials.
• Chemical Research & Development: A versatile synthon for academic and industrial research into new fluorination methodologies and complex molecule construction.
• Fine Chemical Production: Used in custom synthesis and contract manufacturing for specialized, high-value chemical products.

Basic Information

Product Name	2-(3,4-Difluorophenyl)-1-Phenylethanone
CAS No.	845781-26-2
Molecular Formula	C14H10F2O
Molecular Weight	232.23 g/mol
Synonyms	1-(3,4-Difluorophenyl)-2-phenylethanone; 2-Phenacyl-3,4-difluorobenzene; 3',4'-Difluorodeoxybenzoin; Desoxy-3,4-difluorobenzoin; α-Oxo-3,4-difluorobenzeneacetophenone; (3,4-Difluorophenyl)(phenyl)methanone, Ethanone derivative; DFPE
EINECS	Contact for details

Quality Control

Our 2-(3,4-Difluorophenyl)-1-Phenylethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.