Description

3'-Chloro-5'-Fluoro-2-Phenylacetophenone is a high-purity fluorinated and chlorinated aromatic ketone building block, essential for advanced organic synthesis. Its unique halogenated structure makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated phenyl rings.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and ketone functionality.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring new reaction pathways for fluorinated compounds.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals for client projects.

Basic Information

Product Name	3'-Chloro-5'-Fluoro-2-Phenylacetophenone
CAS No.	845781-21-7
Molecular Formula	C14H10ClFO
Molecular Weight	248.68 g/mol
Synonyms	1-(3-Chloro-5-fluorophenyl)-2-phenylethan-1-one; 3-Chloro-5-fluoro-2-phenylacetophenone; 2-Phenyl-1-(3-chloro-5-fluorophenyl)ethanone; 1-(3-Chloro-5-fluorophenyl)-2-phenylethanone; (3-Chloro-5-fluorophenyl)(phenyl)methanone, methylene derivative; α-Phenyl-3-chloro-5-fluorobenzeneacetophenone
EINECS	Contact for details

Quality Control

Our production of 3'-Chloro-5'-Fluoro-2-Phenylacetophenone adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), physical characteristics, and impurity profiles is provided with every shipment to guarantee reliable and reproducible performance in your applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.