Description

3'-Chloro-4'-Fluoro-2-Phenylacetophenone is a high-purity, specialized aromatic ketone building block of significant importance in advanced organic synthesis. Its precise molecular architecture, featuring strategically placed halogen substituents, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its halogenated phenylacetophenone core contributes to biological activity.
• Material Science Research: Serves as a monomer or building block for developing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: An essential reagent for method development, catalysis studies, and exploring new reaction pathways in academic and industrial R&D laboratories.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	3'-Chloro-4'-Fluoro-2-Phenylacetophenone
CAS No.	845781-19-3
Molecular Formula	C14H10ClFO
Molecular Weight	248.68 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)-2-phenylethan-1-one; 3'-Chloro-4'-fluoro-2-phenylethanone; 2-Phenyl-1-(3-chloro-4-fluorophenyl)ethanone; (3-Chloro-4-fluorophenyl)(phenyl)methanone (common misnomer); 3-Chloro-4-fluoro deoxybenzoin; α-Phenyl-3-chloro-4-fluoroacetophenone; 845781-19-3
EINECS	Contact for details

Quality Control

Our 3'-Chloro-4'-Fluoro-2-Phenylacetophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.