Description

2-Chloro-4-Fluorophenylaceton is a versatile fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its value lies in its reactive acetonitrile group and halogen substituents, which make it a key building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials, improving thermal stability and optical properties.
• Organic Synthesis & Research: Employed in academic and industrial R&D for Suzuki-Miyaura and other cross-coupling reactions to create complex, functionalized aromatic compounds.
• Dye & Pigment Manufacturing: Utilized in the synthesis of specialized fluorinated dyes and pigments that offer superior lightfastness and color properties.

Basic Information

Product Name	2-Chloro-4-Fluorophenylaceton
CAS No.	845781-18-2
Molecular Formula	C8H7ClFO
Molecular Weight	188.59 g/mol
Synonyms	2-Chloro-4-fluorobenzeneacetonitrile; (2-Chloro-4-fluorophenyl)acetonitrile; 2-Chloro-4-fluorobenzyl cyanide; α-Chloro-4-fluoro-benzeneacetonitrile; 845781-18-2; 2-Chloro-4-fluoro phenyl acetonitrile; 2-Chloro-4-fluorobenzeneacetonitrile; 4-Fluoro-2-chlorophenylacetonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluorophenylaceton is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment. We adhere to cGMP principles where applicable to support our clients in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.