Description

4-tert-Butyl-3',4'-Difluorobenzophenone is a high-purity, specialized benzophenone derivative characterized by its tert-butyl and difluoro substituents, which impart unique electronic and steric properties. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of complex molecules. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific fluorinated motifs and ketone functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic ketone structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides where the difluorobenzophenone core enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Acts as a precursor or core structure in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Employed as a monomer or cross-linking agent in the production of high-performance polymers with specific thermal and optical properties.
• Organic Synthesis Building Block: Utilized in Suzuki, Heck, and other cross-coupling reactions to construct complex, polyfunctional aromatic systems.
• UV Absorber & Stabilizer Research: Investigated for potential use in the formulation of advanced UV stabilizers and absorbers for coatings and plastics.

Basic Information

Product Name	4-tert-Butyl-3',4'-Difluorobenzophenone
CAS No.	845781-01-3
Molecular Formula	C17H16F2O
Molecular Weight	274.31 g/mol
Synonyms	3',4'-Difluoro-4-tert-butylbenzophenone; 4-(tert-Butyl)-3',4'-difluorobenzophenone; 1-(4-(tert-Butyl)phenyl)-2,3-difluorophenylmethanone; (4-tert-Butylphenyl)(3,4-difluorophenyl)methanone; Benzophenone, 4-tert-butyl-3',4'-difluoro-; 4-tert-Butyl-3',4'-difluorobenzophenone; 4-(1,1-Dimethylethyl)-3',4'-difluorobenzophenone
EINECS	Contact for details

Quality Control

Our 4-tert-Butyl-3',4'-Difluorobenzophenone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.