Description

2-Methylindazole-7-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those containing indazole motifs for oncology, CNS, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in research and development for creating novel herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors for target identification and validation.
• Catalyst & Ligand Development: Utilized to create novel boron-containing ligands for transition metal catalysis.
• Academic & Contract Research: Essential reagent for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	2-Methylindazole-7-Boronic Acid Pinacol Ester
CAS No.	845751-67-9
Molecular Formula	C₁₄H₁₉BN₂O₂
Molecular Weight	258.13 g/mol
Synonyms	2-Methyl-1H-indazol-7-ylboronic acid pinacol ester; 2-Methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methyl-1H-indazole; 2-Methyl-7-boronoindazole pinacol ester; 2-Methylindazole-7-Boronic Acid, Pinacol Ester; B-(2-Methyl-1H-indazol-7-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Methyl-1H-indazole-7-boronic acid pinacol ester; Pinacol 2-Methyl-1H-indazole-7-boronate
EINECS	Contact for details

Quality Control

Every batch of 2-Methylindazole-7-Boronic Acid Pinacol Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), purity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.