Description

4-tert-Butyl-3',5'-Difluorobenzophenone is a specialized difluorobenzophenone derivative, a key intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of high-performance materials and active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorinated aromatic systems into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, especially those requiring fluorinated aromatic ketone motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the tert-butyl and difluoro substituents can influence biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials for displays and lighting applications, where specific fluorine substitution patterns are critical for performance.
• Polymer Modifier: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal, optical, or chemical resistance properties.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex organic molecules via reactions such as Friedel-Crafts acylation, nucleophilic addition, or reduction to corresponding alcohols.
• Photoinitiator Component: Investigated for use in the formulation of UV-curable resins, inks, and coatings, leveraging the benzophenone core's photochemical activity.

Basic Information

Product Name	4-tert-Butyl-3',5'-Difluorobenzophenone
CAS No.	844885-10-5
Molecular Formula	C₁₇H₁₆F₂O
Molecular Weight	274.31 g/mol
Synonyms	4-(tert-Butyl)-3',5'-difluorobenzophenone; 1-(tert-Butyl)-4-(3,5-difluorobenzoyl)benzene; 3',5'-Difluoro-4-tert-butylbenzophenone; (3,5-Difluorophenyl)[4-(tert-butyl)phenyl]methanone; 4-tert-Butyl-3,5-difluorobenzophenone; 4-(1,1-Dimethylethyl)-3',5'-difluorobenzophenone; Benzophenone, 4-(1,1-dimethylethyl)-3',5'-difluoro-
EINECS	Contact for details

Quality Control

Our 4-tert-Butyl-3',5'-Difluorobenzophenone is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with precise internal specifications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.