Description

3-Bromo-3'-Chloro-5'-Fluorobenzophenone is a high-purity, multi-halogenated benzophenone derivative serving as a critical advanced intermediate in modern organic synthesis. This compound is valued for its unique halogen substitution pattern, which provides distinct reactivity and electronic properties for constructing complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Key synthetic intermediate in the research and development of new pharmaceutical compounds, particularly kinase inhibitors and other small-molecule therapeutics.
• Building block for the synthesis of advanced agrochemicals, including herbicides and fungicides, leveraging its halogenated structure.
• Precursor in material science for the creation of specialty polymers and liquid crystals where specific halogen interactions are required.
• Versatile scaffold in academic and industrial organic chemistry for cross-coupling reactions, such as Suzuki and Buchwald-Hartwig aminations.
• Starting material for the preparation of more complex benzophenone-based photoinitiators or UV absorbers.
• Reference standard and impurity marker in analytical chemistry and quality control laboratories for related substance testing.

Basic Information

Product Name	3-Bromo-3'-Chloro-5'-Fluorobenzophenone
CAS No.	844879-45-4
Molecular Formula	C13H7BrClFO
Molecular Weight	313.55 g/mol
Synonyms	3-Bromo-3'-chloro-5'-fluorobenzophenone; Benzophenone, 3-bromo-3'-chloro-5'-fluoro-; 3'-Chloro-5'-fluoro-3-bromobenzophenone; (3-Bromophenyl)(3-chloro-5-fluorophenyl)methanone; 844879-45-4; 3-Br-3'-Cl-5'-F-Benzophenone
EINECS	Contact for details

Quality Control

Our 3-Bromo-3'-Chloro-5'-Fluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.