Description

trans-2-(4-Thiomethylbenzoyl)Cyclohexane-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) where precise molecular architecture is required for efficacy. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly in therapeutic areas requiring complex chiral centers.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex molecular frameworks, leveraging its ketone and carboxylic acid functionalities.
• Protease Inhibitor Development: Serves as a precursor or core structure in the development of enzyme inhibitors, given the potential bioactivity of the thiomethylbenzoyl moiety.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	trans-2-(4-Thiomethylbenzoyl)Cyclohexane-1-Carboxylic Acid
CAS No.	844856-85-5
Molecular Formula	C15H18O3S
Molecular Weight	278.37 g/mol
Synonyms	2-[(4-Methylsulfanyl)benzoyl]cyclohexanecarboxylic acid (trans-); (1r,2r)-2-(4-(Methylthio)benzoyl)cyclohexane-1-carboxylic acid; trans-2-(p-(Methylmercapto)benzoyl)cyclohexanecarboxylic Acid; 4-(Methylthio)benzoylcyclohexanecarboxylic Acid; 844856-85-5; p-(Methylthio)benzoylcyclohexanecarboxylic Acid; Cyclohexanecarboxylic acid, 2-[4-(methylthio)benzoyl]-, trans-
EINECS	Contact for details

Quality Control

Our trans-2-(4-Thiomethylbenzoyl)Cyclohexane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and related substances is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (trans isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.