Description

Methyl (4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Carbamate is a high-purity, synthetically valuable boronic ester derivative. This compound is a critical pharmaceutical intermediate and Suzuki-Miyaura cross-coupling building block, enabling the efficient construction of complex molecules. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed as a tool compound or linker in bioconjugation and probe development.
• Academic & Industrial R&D: Essential reagent for method development and exploratory synthesis in organic chemistry laboratories.
• Scale-up & Process Chemistry: Suitable for optimization and kilogram-scale production under GMP or non-GMP conditions for clinical trial material.

Basic Information

Product Name	Methyl (4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Carbamate
CAS No.	844500-75-0
Molecular Formula	C14H20BNO4
Molecular Weight	277.13 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl methylcarbamate; Methyl N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate; Methyl carbamic acid 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl ester; Pinacol [4-(Methoxycarbonylamino)phenyl]boronate; 4-(Methoxycarbonylamino)phenylboronic acid pinacol ester; B-[4-[(Methoxycarbonyl)amino]phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Methyl (4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.