Description

16-(tert-Butoxy)-16-Oxohexadecanoic Acid is a high-purity, synthetic fatty acid derivative featuring a tert-butoxy ketone moiety. This functionalized long-chain acid serves as a versatile intermediate for advanced organic synthesis, enabling the introduction of both carboxylic acid and protected ketone functionalities. It is particularly valuable for researchers and manufacturers in the pharmaceutical and specialty chemical sectors who require precise building blocks for drug discovery, polymer modification, and the synthesis of complex surfactants or lubricant additives.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring lipophilic chains with ketone or acid handles for further derivatization.
• Specialty Polymer Synthesis: Used as a monomer or co-monomer to create functionalized polyesters, polyamides, or other polymers with tailored properties such as biodegradability or specific surface characteristics.
• Advanced Material Research: Serves as a precursor for surface-active agents, lubricant additives, or corrosion inhibitors where the specific chain length and functional groups are critical for performance.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecular architectures, including macrocycles and dendritic compounds.
• Bioconjugation & Probe Development: The carboxylic acid group allows for coupling to amines or other functional groups, useful in creating fluorescent probes, drug conjugates, or biomaterial coatings.

Basic Information

Product Name	16-(tert-Butoxy)-16-Oxohexadecanoic Acid
CAS No.	843666-27-3
Molecular Formula	C₂₀H₃₈O₄
Molecular Weight	342.52 g/mol
Synonyms	16-(tert-Butoxy)-16-oxohexadecanoic acid; 16-tert-Butoxy-16-oxohexadecanoic acid; Hexadecanoic acid, 16-(1,1-dimethylethoxy)-16-oxo-; 16-(1,1-Dimethylethoxy)-16-oxohexadecanoic acid; 16-(tert-Butoxy)palmitic acid ketone; ω-(tert-Butoxy)-ω-oxohexadecanoic acid
EINECS	Contact for details

Quality Control

Our 16-(tert-Butoxy)-16-Oxohexadecanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FT-IR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. For cGMP or other specific regulatory requirements, please contact our technical sales team to discuss available documentation and quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed when not in use to prevent degradation. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.