Description

3'-Chloro-5'-Fluoroacetophenone is a high-purity fluorinated and chlorinated acetophenone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique halogenated structure makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the chloro-fluoro substitution pattern can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its aromatic ketone functionality.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and as a standard in analytical chemistry.
• Fine Chemical Production: Acts as a building block for synthesizing dyes, pigments, and other performance chemicals requiring specific halogenation.

Basic Information

Product Name	3'-Chloro-5'-Fluoroacetophenone
CAS No.	842140-52-7
Molecular Formula	C8H6ClFO
Molecular Weight	172.58 g/mol
Synonyms	1-(3-Chloro-5-fluorophenyl)ethanone; 3-Chloro-5-fluoroacetophenone; 3-Chloro-5-fluorophenylethanone; 1-Acetyl-3-chloro-5-fluorobenzene; 3-Chloro-5-fluoroacetylbenzene; Ethanone, 1-(3-chloro-5-fluorophenyl)-; 3'-Chloro-5'-fluoroacetophenone
EINECS	Contact for details

Quality Control

Our 3'-Chloro-5'-Fluoroacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.