Description

4-Bromo-1-Fluoro-2-Naphthaldehyde is a high-purity, halogenated naphthalene derivative serving as a versatile and critical building block in advanced organic synthesis. Its unique molecular structure, featuring both bromine and fluorine substituents on the naphthalene aldehyde core, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated naphthalene scaffolds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the bromo-fluoro substitution pattern can enhance biological activity and stability.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and host molecules in OLED device fabrication.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Dye & Sensor Development: Acts as a core structure for synthesizing novel fluorescent probes and chemosensors.
• Academic & Contract Research: A valuable reagent for methodological studies in cross-coupling reactions and halogen dance chemistry.

Basic Information

Product Name	4-Bromo-1-Fluoro-2-Naphthaldehyde
CAS No.	842136-64-5
Molecular Formula	C11H6BrFO
Molecular Weight	253.07 g/mol
Synonyms	1-Fluoro-4-bromo-2-naphthaldehyde; 2-Naphthaldehyde, 4-bromo-1-fluoro-; 4-Bromo-1-fluoro-2-naphthalenecarboxaldehyde; 4-Bromo-1-fluoronaphthalene-2-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-1-Fluoro-2-Naphthaldehyde is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee consistent quality and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.