Description

6-Fluoropyridine-2-Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily needed by pharmaceutical, agrochemical, and advanced materials researchers for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing fluorinated pyridine derivatives with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides containing the fluoropyridine moiety.
• Material Science: Employed in the creation of organic electronic materials, such as ligands for OLEDs and other fluorinated polymers.
• Chemical Research: Serves as a versatile coupling partner in academic and industrial R&D for constructing diverse chemical libraries.
• Ligand Synthesis: Useful for preparing specialized bidentate or monodentate ligands in catalysis and coordination chemistry.

Basic Information

Product Name	6-Fluoropyridine-2-Boronic Acid Pinacol Ester
CAS No.	842136-58-7
Molecular Formula	C11H15BFNO2
Molecular Weight	223.05 g/mol
Synonyms	2-(6-Fluoropyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Fluoro-2-pyridineboronic acid pinacol ester; 6-Fluoro-2-pyridinylboronic acid pinacol ester; 6-Fluoropyridine-2-boronic acid neopentyl glycol ester (common misnomer); 6-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pinacol 6-Fluoropyridine-2-boronate; 6-F-2-PyBpin
EINECS	Contact for details

Quality Control

Our 6-Fluoropyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.