Description

1-Bromo-3-(1,3-Dioxolan-2-Ylmethyl)Benzene is a versatile aromatic building block featuring both a bromo substituent and a protected aldehyde functionality. This compound is essential for advanced organic synthesis, enabling precise molecular construction through selective cross-coupling and functional group transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries to create complex target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring specific aryl-bromide coupling sites.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the dioxolane-protected aldehyde offers strategic synthetic advantages.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands for metal-catalyzed reactions and other catalytic systems.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers that incorporate functionalized aromatic cores.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	1-Bromo-3-(1,3-Dioxolan-2-Ylmethyl)Benzene
CAS No.	842123-87-9
Molecular Formula	C10H11BrO2
Molecular Weight	243.10 g/mol
Synonyms	2-[(3-Bromophenyl)methyl]-1,3-dioxolane; 3-Bromobenzaldehyde Ethylene Acetal; (3-Bromobenzyl)ethylene Acetal; 1,3-Dioxolane, 2-[(3-bromophenyl)methyl]-; 3-Bromobenzaldehyde Acetal; 2-(3-Bromobenzyl)-1,3-dioxolane; α-(3-Bromophenyl)-1,3-dioxolane-2-methane
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(1,3-Dioxolan-2-Ylmethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.