Description

4-(3-Chloro-5-Fluorophenyl)-1-Buten-4-Ol CAS NO 842123-72-2 is a high-purity fluorinated and chlorinated phenyl butenol derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both halogen substituents and an unsaturated alcohol moiety, makes it an exceptionally versatile building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and CNS-active compound libraries.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated aromatic systems.
• Material Science Research: Used in the synthesis of specialty monomers and ligands for advanced polymers and metal-organic frameworks (MOFs).
• Organic Synthesis & Catalysis: A versatile substrate for cross-coupling reactions, halogen-lithium exchange, and other transition metal-catalyzed transformations.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic & R&D: Fundamental research reagent in universities and corporate R&D centers for exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	4-(3-Chloro-5-Fluorophenyl)-1-Buten-4-Ol
CAS No.	842123-72-2
Molecular Formula	C10H10ClFO
Molecular Weight	200.64 g/mol
Synonyms	4-(3-Chloro-5-fluorophenyl)but-3-en-1-ol; 3-Chloro-5-fluorophenylbutenol; 1-Buten-4-ol, 4-(3-chloro-5-fluorophenyl)-; 4-(3-Chloro-5-fluorophenyl)-3-buten-1-ol; 4-(3-Chloro-5-fluorophenyl)but-3-enol
EINECS	Contact for details

Quality Control

Every batch of 4-(3-Chloro-5-Fluorophenyl)-1-Buten-4-Ol is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.