Description

5-Fluoro-7-Methyl-3,4-Dihydronaphthalen-1(2H)-One is a high-purity fluorinated tetralone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the life sciences sector who require reliable, high-quality building blocks for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in therapeutic areas targeting the central nervous system and oncology.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or precursor in the synthesis of specialty polymers and advanced organic materials with tailored electronic properties.
• Academic & R&D Laboratories: Employed in methodological studies and as a standard in fluorination chemistry and heterocyclic compound synthesis.
• Ligand and Catalyst Development: The structural motif is useful for creating novel chiral ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	5-Fluoro-7-Methyl-3,4-Dihydronaphthalen-1(2H)-One
CAS No.	837373-14-5
Molecular Formula	C₁₁H₁₁FO
Molecular Weight	178.20 g/mol
Synonyms	5-Fluoro-7-methyl-1-tetralone; 5-Fluoro-7-methyl-3,4-dihydro-1(2H)-naphthalenone; 7-Methyl-5-fluoro-1-tetralone; 1(2H)-Naphthalenone, 5-fluoro-7-methyl-3,4-dihydro-; 5-Fluoro-7-methyl-3,4-dihydronaphthalen-1-one; 5-Fluoro-7-methyl-α-tetralone
EINECS	Contact for details

Quality Control

Our 5-Fluoro-7-Methyl-3,4-Dihydronaphthalen-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.